hVEGFR2
系統名
C57BL/6Smoc-Kdrtm2(hKDR) Smoc
SMOC番号
NM-HU-00098
維持形態
Repository Live
遺伝子の概要
Gene Symbol
KDR
説明
表現型データ
Figure 1. Expression of mouse KDR and human KDR in C57BL/6 wild type mice and KDR-HU homozygous mice.
Figure 2：In vivo validation of anti-tumor efficacy in a B16F1 tumor-bearing model of humanized KDR mice. The results showed: The drugs targeting human KDR were associated with a very significant anti-tumor, demonstrating that the humanized KDR mice are a good in vivo model for validating the efficacy of drugs targeting human KDR.
Figure 3：In vivo validation of anti-tumor efficacy in a MC38 tumor-bearing model of humanized KDR mice. The results showed: The drugs targeting human KDR were associated with a very significant anti-tumor.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
詳細At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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