hPSGL-1

系統名

C57BL/6Smoc-Selplgem1(hSELPLG)Smoc

SMOC番号

NM-HU-00046

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Selplg

Synonyms

CD162; Psgl1; Selp1; Selpl; Psgl-1

NCBI ID

20345

MGI ID

106689

Ensembl ID

ENSMUSG00000048163

Pubmed

Selplg

Human Ortholog

SELPLG

説明

The endogenous mouse Selplg gene was replaced by human SELPLG gene.
応用分野：Immunotherapy,cancer research,drug screening

表現型データ

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Fig1. Detection of SELPLG expression in spleen by RT-PCR.Wild type：only one band at 539bp with primers F1/R1(mSelplg);Homozygous: only one band at 320bp with primers F2/R2(mSELPLG); Abbr：M,100bp Plus DNA ladder；HO, homozygous; HE, heterozygous; WT, wild type

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Fig2. Detection of hPSGL-1 expression on B cells in blood in hPSGL-1 knockin mice. 

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Fig3. Detection of hPSGL-1 expression on Monocytes and Granulocytes in blood in hPSGL-1 knockin mice. 

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Fig4. Detection of hPSGL-1 expression on B cells in bone morrow in hPSGL-1 knockin mice.

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Fig5. Detection of hPSGL-1 expression on Monocytes and Granulocytes in bone morrow in hPSGL-1 knockin mice.

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Fig6. Detection of hPSGL-1 expression on T cells in bone morrow in hPSGL-1 knockin mice.

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Fig7. Detection of hPSGL-1 expression on NKs and DCs in bone morrow in hPSGL-1 KI mice.

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Fig8. Detection of hPSGL-1 expression on B cells in spleen in hPSGL-1 knockin mice.

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Fig9. Detection of hPSGL-1 expression on Monocytes and Granulocytes in spleen in hPSGL-1 knockin mice.

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Fig10. Detection of hPSGL-1 expression on T cells in thymus in hPSGL-1 knockin mice.

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