hPD-L1/hLAG3

系統名

C57BL/6Smoc-Cd274em1(hPD-L1)Lag3tm1(hLAG3)Smoc

SMOC番号

NM-HU-00137

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol

Synonyms

B7h1， Pdl1， Pdcd1l1，Pdcd1lg1， A530045L16Rik，Ly66， CD223， LAG-3

NCBI ID

60533，16768

MGI ID

1926446，106588

Ensembl ID

ENSMUSG00000016496，ENSMUSG00000030124

Pubmed

Human Ortholog

CD274，LAG3

説明

hPD-L1（NM-HU-00062）was crossed with hLAG3（NM-HU-00049）to generate hPD-L1/hLAG3.
応用分野：Immunotherapy,cancer research,drug screening

表現型データ

pd-l1&lag3.png


Fig1 Splenocytes from homozygous hPDL1/hLAG3 mice were analyzed by flow cytometry after activation. mPDL1+ and mLAG3+ were detectable in wild type (WT) C57BL/6, while hPDL1+ and hLAG3+ cells were detectable in the homozygous hPDL1/hLAG3 mice.

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