hIl5

系統名

C57BL/6JSmo-Il5tm3(hIL5)Smoc

SMOC番号

NM-HU-190001

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
IL5

説明

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.
応用分野:Immune-related

表現型データ

image.png

Fig1. Detection of IL-5 expression in thymus by RT-PCR. Wild type: only one band at 206 bp with primers F1/R1(mIl-5);Homozygous: only one band at 207 bp with primers F2/R2(hIL-5); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

IL5-Hu.png

Fig 2. Expression of human IL5 in the Serum of IL5-HU homozygous mice is detected by Elisa.

IL5-Mu.png

Fig 3. Expression of murine IL5 in the Serum of IL5-HU homozygous mice is detected by Elisa.


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