hPVRIG

系統名

C57BL/6Smoc-Pvrigem1(hPVRIG)/Smoc

SMOC番号

NM-HU-210008

維持形態

Repository Live

PDFを取得

遺伝子の概要

Gene Symbol
Pvrig

Synonyms

Gm36869

NCBI ID

102640920

MGI ID

5596028

Ensembl ID

ENSMUSG00000109713

Pubmed

Pvrig

Human Ortholog

PVRIG

説明

The endogenous mice Pvrig gene was replaced by human PVRIG gene While hPVRIG(2)(Stock No.NM-HU-215013) mice function similarly to hPVRIG mice, for more detailed information please contact our technical advisor.
応用分野：drug screening

表現型データ

image.png

Fig1. Detection of PVRIG expression in spleen by RT-PCR. 

Wild type: only one band at 291 bp with primers F1/R1(mPvrig); Homozygous: only one band at 351 bp with primers F2/R2(hPVRIG); Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig2. Detection of hPVRIG expression in Daudi cells.

image.png

Fig3. Detection of hPVRIG expression in Spleen in hPVRIG KI mice. 

Note. The anti-human CD112R (PVRIG) Antibody cross-reacted with mPVRIG and humanized PVRIG.

image.png

Fig4. Detection of hPVRIG expression in Blood in hPVRIG KI mice. 

Note. The anti-human CD112R (PVRIG) Antibody cross-reacted with mPVRIG and humanized PVRIG.

あなたも好きかも

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

詳細
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

詳細