hIL7R

系統名

C57BL/6JSmo-Il7rtm1(hIL7R)Smoc

SMOC番号

NM-HU-210027

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
Il7r

説明

The endogenous mice Il7r gene was completely or partially replaced by human IL7R gene via ESC targeting.
応用分野:inmmue therapy;drug screening

表現型データ

image.png

Fig.1 Expression analysis of IL7R on T cells in blood and spleen of hIL7R humanized mice. 

Leukocytes were collected from wild-type C57BL/6 mice (female, 7 weeks old) and homozygous hIL7R humanized mice (female, 7 weeks old), and analyzed by flow cytometry with anti-mIL7R and anti-hIL7R. hIL7R was exclusively detectable in hIL7R humanized mice but not in wild-type mice. hIL7R was exclusively detectable on T cells in hIL7R humanized mice, whereas mIL7R was exclusively detectable on T cells in wild-type C57BL/6 mice.


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