hGCGR

系統名

C57BL/6Smoc-Gcgrem(hGCGR)Smoc

SMOC番号

NM-HU-215004

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
Cxcr5

Synonyms

Blr1; Gpcr6; MDR15; CXC-R5; CXCR-5

Chromosome

9

NCBI ID

12145

MGI ID

103567

Ensembl ID

ENSMUSG00000047880

Pubmed

Cxcr5

Human Ortholog

CXCR5

説明

The endogenous mice Gcgr gene was replaced by human GCGR gene.

表現型データ

image.png

Fig1. Detection of GCGR expression in liver by RT-PCR. 

Wild type: only one band at 589 bp with primers F1/R1(mGcgr);

Homozygous: only one band at 501 bp with primers F2/R2(hGCGR).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig2. Detection of hGCGR expression in hGCGR Mice by WB. 

Abbr. M,marker; HO, homozygous; WT, wild type.

Note. The anti-human GCGR Antibody cross-reacted with mouse GCGR and humanized GCGR.

image.png

Fig3. Detection of hGCGR expression in Kidney in hGCGR KI mice

Note. The anti-human GCGR antibody cross-reacted with mouse GCGR and humanized GCGR.

image.png

Fig4. Detection of hGCGR expression in Liver in hGCGR KI mice.

Note. The anti-human GCGR antibody cross-reacted with mouse GCGR and humanized GCGR.


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