Pah-R261Q

系統名

C57BL/6Smoc-Pahem(R261Q)Smoc

SMOC番号

NM-KI-225102

維持形態

Sperm cryopreservation

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遺伝子の概要

Gene Symbol
Pah

Synonyms

AW106920

NCBI ID

18478

MGI ID

97473

Ensembl ID

ENSMUSG00000020051

Pubmed

Pah

Human Ortholog

PAH

説明

These mice carry a R261Q mutation of Pah gene.

表現型データ

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Fig1. Sequencing results of the Pah locus in the wild type and homozygous Pah-R261Q mice.

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Fig2. 5-months-old hom Pah-R261Q mice were no different from their heterozygote counterparts and WT C57BL/6 mice in length and pigmentation.

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Fig3. Detection of PAH expression in kidney and liver in Pah-R261Q mice.

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Fig4. Detection of blood serum concentrations of the metabolites in Pah-R261Q mice by LC-MS

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Table1. Detection of blood serum concentrations of the metabolites in Pah-R261Q mice


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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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