hIL12B/hIL12A

系統名

C57BL/6Smoc-Il12betm3(hIL12B)Il12atm3(hIL12A)Smoc

SMOC番号

NM-XA-240878

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
Il12b

Synonyms

p40， Il-12b， Il12p40， Il-12p40

NCBI ID

16160

MGI ID

96540

Ensembl ID

ENSMUSG00000004296

Pubmed

Il12b

Human Ortholog

IL12B

Human Ortholog Associated Diseases by GWAS 

免疫缺陷、克罗恩病、银屑病

Gene Symbol
Il12a

Synonyms

p35; Ll12a; Il-12a; IL-12p35

NCBI ID

16159

MGI ID

96539

Ensembl ID

ENSMUSG00000027776

Pubmed

Il12a

Human Ortholog

IL12A

説明

The hIL12A(NM-HU-2000056) was crossed with hIL12B(NM-HU-2000057) to generate hIL12B/hIL12A mice.

表現型データ

image.pngFig1. Detection of human IL12P70 and mouse IL12P70 expression in serum by ELISA (n=3). 

Abbr. HO, homozygous; WT, wild type.

Note. hIL12A/hIL12B and C57BL/6 mice were i.p. injected with LPS for 2h.

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