hAPOE2
系統名
C57BL/6Smoc-Apoetm4(hAPOE2)Smoc
SMOC番号
NM-HU-190013
維持形態
Repository Live
遺伝子の概要
Gene Symbol
Apoe
説明
This APOE2 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE2 corresponding sequence by homologous recombination.
応用分野：Immune-related
*Literature published using this strain should indicate: hAPOE2 mice (Cat. NO. NM-HU-190013) were purchased from Shanghai Model Organisms Center, Inc..
表現型データ
Validation data
Fig1. Genotyping of WT , KO & Humanized mice by PCR.
Primer P1/2 Wild type = 342 bp
Primer P3/4 mutant = 332 bp
M：100bp Plus DNA ladder.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
詳細
Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
詳細