hCD27(2)

系統名

C57BL/6Smoc-Cd27tm3(hCD27)Smoc

SMOC番号

NM-HU-190035

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
CD27

Synonyms

Cd27; S152; Tnfrsf7; Tp55

NCBI ID

21940

MGI ID

88326

Ensembl ID

ENSMUSG00000030336

Pubmed

CD27

Human Ortholog

CD27

説明

The endogenous mouse Cd27 gene was replaced by human CD27 gene. While hCD27 mice(Stock No.NM-HU-00093）have been pulled from shelves for some reasons.
応用分野：Immunotherapy,cancer research,drug screening

表現型データ

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Fig1. Detection of hCD27 expression on T cells in spleen in heterozygous hCD27 kncokin mice.

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Fig2. Detection of hCD27 expression on T cells in peripheral blood in heterozygous hCD27 knockin mice.

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Fig3. Detection of hCD27 expression on T cells in bone marrow in heterozygous hCD27 knockin mice.

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Fig4. Detection of hCD27 expression on T cells in spleen in homozygous hCD27 knockin mice.

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Fig5. Detection of hCD27 expression on T cells in bone marrow in homozygous hCD27 knockin mice.

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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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