Eif4ebp2-KO

系統名

C57BL/6Smoc-Eif4Ebp2em1Smoc

SMOC番号

NM-KO-191121

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Eif4ebp2

Synonyms

4E-BP2， PHAS-II， AA792569， BC010348， 2810011I19Rik

NCBI ID

13688

MGI ID

109198

Ensembl ID

ENSMUSG00000020091

Pubmed

Eif4ebp2

Human Ortholog

EIF4EBP2

説明

Exon 3-4 of Eif4ebp2 gene was deleted to generate Eif4ebp2 knockout mice.
応用分野：Cell proliferation and differentiation, viral infection, nervous system, synaptic transmission, autism, muscle homeostasis

病気の予測

Autism Spectrum Disorder

表現型

MGI:3610950

参考文献

Gkogkas CG, Khoutorsky A, Ran I, Rampakakis E, Nevarko T, Weatherill DB, Vasuta C, Yee S, Truitt M, Dallaire P, Major F, Lasko P, Ruggero D, Nader K, Lacaille JC, Sonenberg N, Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature. 2013 Jan 17;493(7432):371-7

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