hNCR3

系統名

C57BL/6Smoc-Ncr1em1(hNCR3)Smoc

SMOC番号

NM-HU-215066

維持形態

Sperm cryopreservation

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遺伝子の概要

Gene Symbol
Ncr1

Synonyms

Ly94; NKp46

NCBI ID

17086

MGI ID

1336212

Ensembl ID

ENSMUSG00000062524

Pubmed

Ncr1

Human Ortholog

NCR1

説明

The endogenous mouse Ncr1 gene was replaced by human NCR3 gene.

表現型データ

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Fig1. Detection of NCR3 expression in spleen by RT-PCR. Wild type: only one band at 230 bp with primers F1/R1(mNcr1);Heterozygous: one band at 230 bp with primers F1/R1(mNcr1) and one band at 291 bp with primers F2/R2(hNCR3); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Analysis of hNCR3(CD337) expression on NK cells in PB by FACS.

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Fig3. Analysis of hNCR3(CD337) expression on NK cells in spleen by FACS.

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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