Trp63-CreERT2

系統名

C57BL/6Smoc-Trp63em(CreERT2-WPRE-polyA)Smoc

SMOC番号

NM-KI-225021

維持形態

Sperm cryopreservation

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遺伝子の概要

Gene Symbol
Trp63

Synonyms

Ket; P63; P73l; Tp63; P51/P63; AI462811; Trp53rp1

NCBI ID

22061

MGI ID

1330810

Ensembl ID

ENSMUSG00000022510

Pubmed

Trp63

Human Ortholog

-

説明

A CreERT2-Wpre-polyA expression cassette was knocked into the exon4 of Trp63 gene via CRISPR/Cas mediated recombination.

表現型データ

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Fig1. Cre mediated recombination in bladder of Trp63CreERT2/+;Rosa26tdTomato/+ mouse. 

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Fig2. Detection of tdTomato(red) in various tissues of Trp63CreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: bladder, skin, cornea, stomach, salivary gland, thymus. A few cells expressed in kidney and spleen. Tissues that unexpressed include brain, spinal cord, heart, lung, liver, brown fat, pituitary, pancreas, small intestine, colon, ovary and uterus, skeletal muscle, adrenal gland. (53-day old, female) (For more detailed information please contact our technical advisor.) 

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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