Prlr-KO

系統名

C57BL/6Smoc-Prlrem1Smoc

SMOC番号

NM-KO-200430

維持形態

Developing

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遺伝子の概要

Gene Symbol
Prlr

Synonyms

Pr-1， Pr-3， AI987712， Prlr-rs1

NCBI ID

19116

MGI ID

97763

Ensembl ID

ENSMUSG00000005268

Pubmed

Prlr

Human Ortholog

PRLR

説明

Prlr-KO mice(Stock No.NM-KO-200430）carry a knockout allele derived from the targeted deletion of exon 4. While Prlr-KO(2) mice(Stock No.NM-KO-210387）carrying the exon 5 deletion.
応用分野：Therapeutic antibody target

病気の予測

Familial Medullary Thyroid Carcinoma

表現型

MGI:4431029

参考文献

Ormandy CJ, et al., Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse. Genes Dev. 1997 Jan 15;11:167-78

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