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Models

About 42,523 results
マウス

hPVRL2

系統名：C57BL/6Smoc-Nectin2tm1(hNECTIN2)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000084

The endogenous mouse Nectin2 gene was replaced by human PVRL2 gene.

マウス

Hopx-2A-DreERT2

系統名：C57BL/6Smoc-Hopxem1(2A-DreERT2)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-190035

A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site.

マウス

hTP53(2)

系統名：C57BL/6Smoc-Trp53tm1(hTP53)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-225052

The endogenous mouse Trp53 gene was replaced by human TP53 gene.

マウス

Lyz2-2A-CreERT2

系統名：C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-18018

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

マウス

hTIGIT(3)

系統名：C57BL/6Smoc-Tigittm3(hTIGIT)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200244

The endogenous mouse Tigit gene was replaced by human TIGIT gene. While hTIGIT(Stock No.NM-HU-00053) mice function similarly to hTIGIT（3） mice ,for more detailed information please contact our technical advisor.

マウス

Col1a1-TRE3G-dCas9-VPR-EGFP

系統名：C57BL/6Smoc-Col1a1em1(TRE3G-dCas9-VPR-eGFP-pA)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-00123

These mice harbor a TRE3G-dCas9-VPR(VP64-p65-Rta)-eGFP-pA tetracycline-controlled transcriptional activation cassette in mouse Col1a1 loci. This strain can be used in CRISPR mediated target gene transcriptional activation (CRISPRa).

マウス

Isl1-CreERT2

系統名：C57BL/6Smoc-Isl1em1(CreERT2) Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-00013

CreERT2 was inserted at the start codon (ATG site). The KI mice have a tamoxifen-inducible cre-mediated recombination system.

マウス

Axin2-CreERT2

系統名：C57BL/6Smoc-Axin2em1(CreERT2-pA)Smoc
維持形態：Developing | SMOC番号：NM-KI-200109

A CreERT2-pA expression cassette was knocked into the Axin2 gene start codon site. As Axin2 is an intracellular protein, it is essential for identifying a surface marker for stem cell purification. When these Axin2-CreERT2 mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the flanked sequences in Axin2 expressing cells.

マウス

hSIGLEC15

系統名：C57BL/6Smoc-Siglec15em1(hSIGLEC15)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-190037

The endogenous mouse Siglec15 gene was replaced by human SIGLEC15 gene.

マウス

hTNFR2/hFCGR2B

系統名：C57BL/6Smoc-Tnfrsf1bem2(hTNFRSF1B)Fcgr2bem3(FCGR2B)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210404

hTNFRSF1B (NM-HU-190010) was crossed with hFCGR2B (NM-HU-2000010) to generate hTNFRSF1B/hFCGR2B mice.

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