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Models

About 42,523 results
マウス

hTNFRSF10B

系統名：C57BL/6Smoc-Tnfrsf10bem1(hTNFRSF10B)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210005

The endogenous mice Tnfrsf10B gene was replaced by human TNFRSF10B gene

マウス

hIL2/hIL2RA/hIL2RB/hIL2RG

系統名：C57BL/6Smoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210415

hIL2/hIL2RA(NM-HU-200275) was crossed with hIL2RA/hIL2RB/hIL2RG(NM-HU-210414) to generate hIL2/hIL2RA/hIL2RB/hIL2RG mice.

マウス

hMERTK

系統名：C57BL/6Smoc-Mertkem1(hMERTK)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000031

The endogenous mouse Mertk gene was replaced by human MERTK gene.

マウス

hPD-1/hCTLA-4

系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Ctla4em1(hCTLA4)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-00079

hPD-1(NM-HU-00015) was crossed with hCTLA4(NM-HU-00014)to generate hPD-1/hCTLA4 mice

マウス

Foxp3-V5-AviTag-IRES-Luc-2A-tdTomato

系統名：C57BL/6Smoc-Foxp3em1(V5-AviTag-IRES-luci-2A-tdTomato)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-18034

A V5-AviTag-IRES-luci-2A-tdTomato expression cassette was inserted before the stop codon TGA of mouse Foxp3 gene to establish a multi-labeled knockin model with V5, Avi, luciferase and tdTomato fluorescent protein.

マウス

Calca-Cre

系統名：C57BL/6Smoc-Calcaem1(iCre-2A)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-200302

iCre-2A expression cassette was knocked into the Calca gene start codon site.

マウス

hGPR75

系統名：C57BL/6Smoc-Gpr75em1(hGPR75)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-215056

The endogenous mouse Gpr75 gene was replaced by human GPR75 gene.

マウス

hCTLA-4/4-1BB

系統名：C57BL/6Smoc-Ctla4em1(hCTLA4) Tnfrsf9em1(hTNFRSF9) /Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-18020

This CTLA4 and 4-1BB double knockin strain is established by crossing CTLA4-HU and 4-1BB-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

マウス

Il18-Luc-2A-EGFP

系統名：C57BL/6Smoc-Il18em1(Luc-eGFP)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-00032

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il18.

マウス

hCD52

系統名：C57BL/6Smoc-Cd52em1(hCD52)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000058

The endogenous mouse Cd52 gene was replaced by human CD52 gene.

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