Sftpc-IRES-rtTA
系統名
C57BL/6Smoc-Sftpcem2(Avitag-IRES-V5-M2rtTA-WPRE-polyA)Smoc
SMOC番号
NM-KI-18043
維持形態
Repository Live
遺伝子の概要
Gene Symbol
Sftpc
説明
表現型データ
Fig1. Expression Pattern of EGFP in Sftpc -M2rtTA; pTRE-H2BGFP mice.
Sftpc -M2rtTA mice express the reverse tetracycline-controlled transactivator (rtTA) protein under the control of the mouse surfactant, pulmonary-associated protein C (Sftpc) promoter, and expression of the target gene may be regulated by the tetracycline analog, doxycycline. This strain provides a Tet-On tool that allows the inducible expression of genes in the developing and adult lung and respiratory epithelium.
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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