Acta2-CreERT2

系統名

C57BL/6Smoc-Acta2em1(CreERT2-Wpre-polyA)Smoc

SMOC番号

NM-KI-200074

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
Acta2

説明

A CreERT2-Wpre-polyA expression cassette was knocked into the Acta2 gene start codon site.
応用分野:These mice express cre recombinase from the Acta2 locus. This strain may be useful for studying the function of smooth muscle.

表現型データ

NM-KI-200074;Acta2-CreERT2-1.png

Fig. 1 CreERT2-mediated recombination in the pancreas of Acta2CreERT2 /+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the vascular smooth muscle cells of Acta2 CreERT2 /+; Rosa26tdTomato/+ mouse after tamoxifen treatment. Some leakiness were detected prior to tamoxifen exposure. 

NM-KI-200074;Acta2-CreERT2-2.png

Fig. 2 Detection of tdTomato(red) in various tissues of Acta2CreERT2/+; Rosa26tdTomato/+ mice. CreERT2 mediated recombination can be detected in the pancreas, kidney, brain, heart, lung, liver, thymus, submandibular gland, brown fat, ovary, muscle, thymus, spleen, large intestine and small intestine. Leakiness were detected in the above tissues prior to tamoxifen exposure. Tdtomato expression can not be observed in the pituitary gland. (For more detailed information please contact our technical advisor.)


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