Arc-CreERT2
系統名
C57BL/6Smoc-Arcem1(CreERT2-SV40-pA)Smoc
SMOC番号
NM-KI-200101
維持形態
Embryo cryopreservation
遺伝子の概要
Gene Symbol
Arc
説明
表現型データ
Fig.1 Detection of tdTomato (red) in the brain of ArcCreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment. CreERT2-mediated recombination in the brain can be induced by tamoxifen. Some leakiness were detected in the hippocampus and thalamus prior to tamoxifen exposure.
Fig. 2 Detection of tdTomato (red) in various tissues of ArcCreERT2/+; Rosa26tdTomato/+ mice. CreERT2-mediated recombination in the brain, liver, kidney, pancreas, lung, stomach, submandibular gland, skin, testis and epididymis, pituitary gland and eye can be induced by tamoxifen. Some leakiness were detected in the brain and brown fat prior to tamoxifen exposure. (For more detailed information please contact our technical advisor.)
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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