Trpv1-IRES-Cre

系統名

C57BL/6Smoc-Trpv1em1(Myc-IRES-Cre)Smoc

SMOC番号

NM-KI-200139

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
Trpv1

説明

A Myc-IRES-Cre expression cassette was knocked into the Trpv1 gene stop codon site. Trpv1 is known as transient receptor potential cation channel, subfamily V, member 1. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying the pain caused by heat and capsaicin.
応用分野:Cre recombinase tool

表現型データ

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Fig. 1 Cre-mediated recombination in the brain of Trpv1Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the dentate gyrus of Trpv1Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of  Trpv1Cre/+; Rosa26tdTomato/+ mice. Tdtomato is expressed in the brown fat, pancreas, kidney, retina, brain, pituitary gland, heart, lung, liver, stomach, salivary gland and skin. Tdtomato expression can also be observed in individual cells of the testis, epididymis, muscle, spleen, thymus, intestine and colon. (For more detailed information please contact our technical advisor.)



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