Drd1-2A-CreERT2

系統名

C57BL/6Smoc-Drd1em1(2A-CreERT2-WPRE-pA)Smoc

SMOC番号

NM-KI-18016

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
Drd1

Synonyms

Drd-1; Drd1a; Gpcr15; C030036C15Rik

NCBI ID

13488

MGI ID

99578

Ensembl ID

ENSMUSG00000021478

Pubmed

Drd1

Human Ortholog

DRD1

説明

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Drd1 gene via homologous recombination to establish a tamoxifen inducible Drd1-CreERT2 tool stain. This strain can be used to knockout target gene in Drd1+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.
応用分野：Cre recombinase tool

表現型データ

验证数据-Drd1a-CreERT2-图片1.png

Figure 1：CreERT2-mediated recombination in brain of Drd1a CreERT2; R26 tdTomato mice. Detection of tdTomato (red) in brain of Drd1a CreERT2; R26 tdTomato mice.

验证数据-Drd1a-CreERT2-图片2.png

Figure 2：CreERT2-mediated recombination in CPU(corpus striatum) of Drd1a CreERT2; R26 tdTomato mice. Detection of tdTomato (red) in CPU of Drd1a CreERT2; R26 tdTomato mice.

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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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