Lyz2-2A-CreERT2
系統名
C57BL/6Smoc-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
SMOC番号
NM-KI-18018
維持形態
Repository Live
遺伝子の概要
Gene Symbol
Lyz2
説明
A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.
応用分野：Cre recombinase tool
*Literature published using this strain should indicate: Lyz2-2A-CreERT2 mice (Cat. NO. NM-KI-18018) were purchased from Shanghai Model Organisms Center, Inc..
表現型データ
Fig1 Evaluation of CreERT2 recombination in Lyz2 Cre+/-;R26 tdT+/- mice.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
詳細
Milestones
Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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