Cdh1-2A-DreERT2

系統名

C57BL/6Smoc-Cdh1em3(2A-DreERT2)Smoc

SMOC番号

NM-KI-190031

維持形態

Sperm cryopreservation

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遺伝子の概要

Gene Symbol
Cdh1

Synonyms

Um; UVO; Ecad; ARC-1; E-cad; L-CAM; AA960649

NCBI ID

12550

MGI ID

88354

Ensembl ID

ENSMUSG00000000303

Pubmed

Cdh1

Human Ortholog

CDH1

説明

A 2A-DreERT2 expression cassette was knocked into the Cdh1 gene stop codon site via CRISPR/Cas mediated recombination.
応用分野：Dre recombinase tool

表現型データ

image.png

Fig. 1 DreERT2-mediated recombination in the liver of Cdh1DreERT2/+；R26tdtomato/+ mouse. Tdtomato (red) expression can be detected in the liver after tamoxifen treatment. Cdh1 gene encodes E-cadherin(E-CAD), a calcium-dependent adhesion  molecule that expressed primarily in epithelial cells. (Documented in the following reference.)


出版物

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
References：CELL STEM CELL

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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