Atp4b-IRES-CreERT2

系統名

C57BL/6Smoc-Atp4bem1(IRES-CreERT2-WPRE-pA)Smoc

SMOC番号

NM-KI-210118

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Atp4b

Synonyms

AV080843

NCBI ID

11945

MGI ID

88114

Ensembl ID

ENSMUSG00000031449

Pubmed

Atp4b

Human Ortholog

ATP4B

説明

An IRES-CreERT2-WPRE-pA expression cassette was knocked into the Atp4b gene start codon site.Besides,An IRES-CreERT2 expression cassette were knock into the Bhlha15 gene stop codon site to generate Atp4b-IRES-CreERT2(2)(Stock No. NM-KI-210119) mice.
応用分野：Cre tool mice

表現型データ

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Fig1. CreERT2-mediated recombination in the stomach of Atp4bCreERT2/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the stomach of Atp4bCreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment. Some leakiness was detected prior to tamoxifen exposure.

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Fig2. Detection of tdTomato (red) in various tissues of  Atp4bCreERT2/+; Rosa26tdTomato/+ mice after tamoxifen treatment. Tdtomato was expressed in the glandular stomach. Tdtomato can also be detected in the pituitary, thymus, salivary glands, brown adipose tissue, spleen, pancreas, and muscle. Some leakiness was detected prior to tamoxifen exposure. TdTomato expression can not be detected in the brain, liver, lung, large intestine, small intestine, kidney or skin.

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