Gpr65-IRES-Cre

系統名

C57BL/6Smoc-Gpr65em1(IRES-iCre)Smoc

SMOC番号

NM-KI-200135

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol

Synonyms

Dig1， TDAG8， Gpcr25

NCBI ID

14744

MGI ID

108031

Ensembl ID

ENSMUSG00000021886

Pubmed

Human Ortholog

GPR65

説明

A IRES-iCre expression cassette was knocked into the Gpr65 gene stop codon site.
応用分野：Cre recombinase tool; The G-protein-coupled receptor(GPR65) neurons  innervate intestinal villi and gastric mucosa to sense nutrients. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre.

表現型データ

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Fig. 1 Cre-mediated recombination in the intestine of Gpr65Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the large intestine and small intestine derived from Gpr65Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of Gpr65Cre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the pituitary gland, heart, liver, lung, stomach, salivary gland, kidney, pancreas, large intestine, skin, testis and epididymis. TdTomato can also be detected in individual cells of the thymus and spleen. Tdtomato expression can not be observed in brown fat. (For more detailed information please contact our technical advisor.)


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