Nmu-2A-Cre

系統名

C57BL/6Smoc-Nmuem1(2A-Cre-WPRE-polyA)Smoc

SMOC番号

NM-KI-200298

維持形態

Repository Live

PDFを取得

遺伝子の概要

Gene Symbol
Nmu

Synonyms

-

NCBI ID

56183

MGI ID

1860476

Ensembl ID

ENSMUSG00000029236

Pubmed

Nmu

Human Ortholog

NMU

説明

2A-Cre-WPRE-polyA expression cassette was knocked into the Nmu gene stop codon site. Nmu gene encodes a member of the neuromedin family of neuropeptides. The encoded protein plays a role in energy homeostasis and body temperature regulation. And the protein is homologous with human NMU, which is linked toobesity.
応用分野：Cre recombinase tool; Neuroscience

表現型データ

image.png

Fig. 1 Cre-mediated recombination in the intestine of NmuCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the submucosal plexus (red arrows) of NmuCre/+; Rosa26tdTomato/+ mouse.

image.png

Fig. 2 Cre-mediated recombination in the intestine of NmuCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the substantia nigra pars reticulate(SNR) of NmuCre/+; Rosa26tdTomato/+ mouse.

image.png

Fig. 3 Detection of tdTomato(red) in various tissues of NmuCre/+; Rosa26tdTomato/+ mice. Cre-mediated recombination can be detected in some cells of the heart, intestine, colon, pancreas, ovary, uterus, thymus, stomach. Tdtomato can also be detected in individual cells of the brown fat, kidney, lung, liver, muscle, salivary gland, skin and spleen. (For more detailed information please contact our technical advisor.)


あなたも好きかも

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

詳細
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

詳細