hFCGRT(NMG)

系統名

NOD-PrkdcscidIl2rgem1Fcgrtem2(FCGRT)Smoc

SMOC番号

NM-NSG-020

維持形態

Repository Live

PDFを取得

遺伝子の概要

Gene Symbol
Fcgrt

説明

The background of this strain is NMG, and its endogenous Fcgrt gene is replaced with human FCGRT.

応用分野:Immunotherapy,cancer research,drug screening

表現型データ

image.png

Fig.1 Detection of FCRN expression in kidney by RT-PCR. 

Wild type: only one band at 181 bp with primers F1/R1(mFcgrt);

Heterozygous: one band at 181 bp with primers F1/R1(mFcgrt) and one band at 310 bp with primers F2/R2(hFCGRT). 

Abbr. M, DNA marker; HE, heterozygous; WT, wild type.

image.png

Fig.2 Detection of human FCRN expression in hFCRN (NMG) mice by WB. 

Abbr. M, marker; WT1, wild type, NOD-Scid; WT2, wild type, NMG; HE, heterozygous; PC, positive control, hFCRN (NM-HU-190070).



あなたも好きかも

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

詳細
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

詳細