hALB/hFCRN
系統名
C57BL/6Smoc-Albem3(hALB)Fcgrtem2(hFCGRT)/Smoc
SMOC番号
NM-HU-200278
維持形態
Repository Live
遺伝子の概要
Gene Symbol
FCGRT
Gene Symbol
ALB
Gene Symbol
Fcgrt
説明
表現型データ
Fig.1 Detection of hALB (A) and mALB (B) expression in serum by ELISA (n=3).
Abbr. HO, homozygous; WT, wild type.
Fig.2 Expression characterization of hFCRN in hALB/hFCRN dKI mice by Western blot. (Arrow indicates expected molecular weight and asterisk indicates a nonspecific band)
Fig.3 In vivo PK profiles of TAA scfv-anti HSA VHH in hALB/hFCRN mice (female, 10-12weeks, n=3 mice/timepoint).
(In cooperation with the third party).
Fig.4 Blood concentration curves of test articles in C57BL/6 and hFcRn/hALB dKI mice. (In cooperation with the third party)
Table 1 Noncompartmental Analysis (NAC) results of test articles in hFcRn/hALB dKI mice. (In cooperation with the third party)
Fig.5 Fitting curves of blood concentration in C57BL/6 and hFcRn/hALB dKI mice. (In cooperation with the third party)
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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