Lyz2-IRES-DTRGFP

系統名

C57BL/6Smoc-Lyz2em3(IRES-DTREGFP)Smoc

SMOC番号

NM-KI-190041

維持形態

Repository Live

PDFを取得

遺伝子の概要

Gene Symbol
Lyz2

Synonyms

Lys; Lzm; Lzp; Lysm; Lyzs; Lyzf2; Lzm-s1; AI326280

NCBI ID

17105

MGI ID

96897

Ensembl ID

ENSMUSG00000069516

Pubmed

Lyz2

Human Ortholog

LYZ2

説明

A IRES-DTREGFP expression cassette was knocked into the Lyz2 gene stop codon site.
応用分野：DTR mouse

表現型データ

1.png

Fig1. Analysis of GFP expression by FACS . The Lyz2-DTRGFP mouse expresses GFP on CD11b+ cells.


2.png

Fig2. Analysis of the level of different immune cells in PBMC by FACS (See Figure 4 for details of diphtheria toxin injection). 


3.png

Fig3. Analysis of the level of different immune cells in the spleen and transplanted tumor by FACS (See Figure 4 for details of diphtheria toxin injection). 

4.png

Fig4. The growth of MC38 tumors in Lyz2-DTRGFP mice and C57BL/6 mice. 

Heterozygous Lyz2-DTRGFP mice and C57BL/6 mice were inoculated with MC38 colon cancer cells.  The Lyz2-DTRGFP mice were injected with diphtheria toxin twice a week.

 The data is provided by Crownbio.

あなたも好きかも

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

詳細
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

詳細