Cd19-IRES-DTRGFP
系統名
C57BL/6Smoc-Cd19em2(IRES-DTREGFP)Smoc
SMOC番号
NM-KI-190042
維持形態
Embryo cryopreservation
遺伝子の概要
Gene Symbol
CD19
説明
表現型データ
Validation data of EGFP expression
Fig1. Validation EGFP expression in PBMC by FACS. (Cooperation with CrownBio)
Validation data of DTR function
Heterozygous Cd19-IRES-DTRGFP mice and C57BL/6 mice were inoculated with MC38 colon cancer cells. After the tumors grew to 100 mm3, the Cd19-IRES-DTRGFP mice were injected with Diphtheria toxin.
Fig2. The growth of MC38 tumors in Heterozygous Cd19-IRES-DTRGFP mice and C57BL/6 mice. (Cooperation with CrownBio)
Fig3. The percent of CD19+ cell in peripheral blood of MC38 tumor-bearing Cd19-IRES-DTRGFP mice and C57BL/6 mice is detected by FACS. (Cooperation with CrownBio)
Fig4. The percent of CD19+ cell in peripheral blood of MC38 tumor-bearing Cd19-IRES-DTRGFP mice and C57BL/6 mice is detected by FACS. (Cooperation with CrownBio)
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
詳細Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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