hDMPK
系統名
C57BL/6Smoc-Dmpktm1(hDMPK)Smoc
SMOC番号
NM-HU-225084
維持形態
Repository Live
遺伝子の概要
Gene Symbol
Dmpk
説明
The endogenous mouse Dmpk gene was replaced by human DMPK gene.
表現型データ
Fig.1 Detection of DMPK expression in heart by RT-PCR.
Wild type: only one band at 259 bp with primers F1/R1(mDmpk);
Homozygous: only one band at 324 bp with primers F2/R2(hDMPK).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of human DMPK expression in hDMPK knockin mice by WB.
Abbr. M, marker; WT, wild type; HO, Homozygous; PC, hela cells.
Note. The anti-human DMPK antibody cross-reacted with mouse DMPK and humanized DMPK. Arrow indicates expected molecular weight and asterisk indicates a nonspecific band.
あなたも好きかも
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
詳細At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
詳細