Ncr1-IRES-DTRGFP

系統名

C57BL/6Smoc-Ncr1em1(IRES-DTREGFP)Smoc

SMOC番号

NM-KI-190044

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Ncr1

Synonyms

Ly94; NKp46

NCBI ID

17086

MGI ID

1336212

Ensembl ID

ENSMUSG00000062524

Pubmed

Ncr1

Human Ortholog

NCR1

説明

A IRES-DTREGFP expression cassette was knocked into the Ncr1 gene stop codon site.
応用分野：DTR mouse

表現型データ

Heterozygous Ncr1-IRES-DTRGFP mice and C57BL/6 mice were inoculated with MC38 colon cancer cells. After the tumors grew to 100 mm3, Ncr1-IRES-DTRGFP  mice were injected with Diphtheria toxin. 

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Fig1. The growth of MC38 tumors in Heterozygous Ncr1-IRES-DTRGFP mice and C57BL/6 mice. (Cooperation with CrownBio)

Ncr1-2.png

Fig2. The percent of NK cell in peripheral blood of MC38 tumor-bearing Ncr1-IRES-DTRGFP mice and C57BL/6 mice is detected by FACS.(Cooperation with CrownBio)

Ncr1-3.png

Fig3. The percent of NK cell in peripheral blood of MC38 tumor-bearing Ncr1-IRES-DTRGFP mice and C57BL/6 mice is detected by FACS.(Cooperation with CrownBio)

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