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Models

About 42,523 results
マウス

hCD19/hCD3E

系統名：C57BL/6Smoc-Cd19em1(hCD19)Cd3eem1(hCD3E)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190027

This CD19 and CD3E double knockin strain is established by crossing CD19-HU and CD3E-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

マウス

Rag2-KO

系統名：C57BL/6Smoc-Rag2em2Smoc
維持形態：Repository Live | SMOC番号：NM-KO-190429

Partial exon 3 of Rag2 gene was deleted to generate Rag2 knockout mice. Deletion of this region will cause frameshift and result in loss of function of mouse Rag2 gene.

マウス

hCD20(2)

系統名：C57BL/6Smoc-Ms4a1tm2 (hCD20)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-200114

Extracellular and transmembrane region of the endogenous mouse Ms4a1 gene was replaced by corresponding region of human CD20 gene. While hCD20(Stock No.NM-HU-190068) mice function similarly to hCD20(2) mice,for more detailed information please contact our technical advisor.

マウス

hCCR8/hCTLA-4

系統名：C57BL/6Smoc-Ccr8em1(hCCR8)Ctla4em1(hCTLA4)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210435

hCCR8(NM-HU-190053) was crossed with hCTLA4(NM-HU-00014) to generate hCCR8/hCTLA4 mice.

マウス

Aicda-Cre

系統名：C57BL/6Smoc-Aicdaem1(Cre-WPRE-polyA)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-200160

A Cre-WPRE-polyA expression cassette was knocked into the Aicda gene start codon site.

マウス

hSEMA4D

系統名：C57BL/6Smoc-Sema4dem1(hSEMA4D)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-00117

The endogenous mouse Sema4d gene was replaced by human SEMA4D gene.

マウス

Muc2-2A-CreERT2-IRES-tdTomato

系統名：C57BL/6Smoc-Muc2em1(2A-CreERT2-tdTomato-Wpre-pA)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-200301

2A-CreERT2-tdTomato-Wpre-pA expression cassette was knocked into the Muc2 gene stop codon site.

マウス

Ahi1-Flox

系統名：B6;129S-Ahi1tm1(flox)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-CKO-00053

These mice possess loxP sites on either side of exon 3 the Ahi1 (Abelson helper integration site 1) gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of the gene.

マウス

hTLR9/hOX40

系統名：C57BL/6Smoc-Tlr9tm1(hTLR9)Tnfrsf4em3(hTNFRSF4)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-190024

This TLR9 and OX40 double knockin strain is established by crossing TLR9-HU and OX40-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

マウス

hCD24/hSIGLEC10

系統名：C57BL/6Smoc-Cd24atm1(hCD24)Siglecgtm1(hSIGLEC10)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-210367

hCD24(NM-HU-2000060) was crossed with hSIGLEC10(NM-HU-2000061）to generate hCD24/hSIGLEC10 mice.

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