Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Immunodeficient NMG Mice
系統名：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Ccr8em1(hCCR8)/Smoc 維持形態：Developing | SMOC番号：NM-HU-210402
hPD-1(NM-HU-00015) and hPD-1(2)(NM-HU-190039) were crossed with hCCR8(NM-HU-190053) to generate hPD-1/hPD-L1(2)/hCCR8 mice.
系統名：C57BL/6Smoc-Cd33em3(CD33)Smoc 維持形態：Repository Live | SMOC番号：NM-HU-200002
The endogenous mouse Cd33 gene was replaced by human CD33 gene .
系統名：C57BL/6Smoc-Ctla4em1(hCTLA4)Cd274em1(hPD-L1)Smoc 維持形態：Embryo cryopreservation | SMOC番号：NM-HU-00102
hPD-L1(NM-HU-00062) was crossed with hCTLA4(NM-HU-00014)to generate hPD-1/hCTLA4 mice
系統名：C57BL/6Smoc-Cd274em1(hPD-L1)Tnfrsf9tm2(h4-1BB)Smoc 維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200260
hPD-L1(NM-HU-00062) was crossed with h4-1BB(2)(NM-HU-190077) to generate hPD-L1/h4-1BB(2).
系統名：C57BL/6Smoc-Appem1Smoc 維持形態：Sperm cryopreservation | SMOC番号：NM-KO-190444
exon 3 of App gene was deleted to generate App knockout mice.
系統名：C57BL/6Smoc-Igs2em1(CAG-LSL-ZsGreen-wpre-pA-CAG-RSR-tdTomato-wpre-pA)Smoc 維持形態：Repository Live | SMOC番号：NM-KI-200319
A CAG-LSL-ZsGreen-wpre-pA-CAG-RSR-tdTomato-wpre-pA expression cassette was knocked into the H11 locus.
系統名：C57BL/6Smoc-Tmem173tm1(hTMem173)Cd274em1(hCD274)Smoc 維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000105
hPD-L1(NM-HU-00062) was crossed with hSTING(NM-HU-190036) to generate hPD-L1/hSTING.
系統名：C57BL/6Smoc-Il12atm3(hIL12A)/Smoc 維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000056
The endogenous mouse Il12a gene was replaced by human IL12A gene.
系統名：C57BL/6Smoc-Adkem1Smoc 維持形態：Embryo cryopreservation | SMOC番号：NM-KO-201237
Exon 4 of Adk gene was deleted to generate Adk knockout mice.
系統名：C57BL/6Smoc-Tigittm3(hTIGIT)Tnfrsf1bem2(hTNFRSF1B)/Smoc 維持形態：Embryo cryopreservation | SMOC番号：NM-HU-210371
hTIGIT(3)(NM-HU-200244) was crossed with hTNFRSF1B(NM-HU-190010）to generate hTIGIT(3)/hTNFRSF1B mice
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