Calb2-IRES-Cre

系統名

C57BL/6Smoc-Calb2em1(IRES-iCre-SV40-pA)Smoc

SMOC番号

NM-KI-200102

維持形態

Sperm cryopreservation

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遺伝子の概要

Gene Symbol
Calb2

Synonyms

CR

NCBI ID

12308

MGI ID

101914

Ensembl ID

ENSMUSG00000003657

Pubmed

Calb2

Human Ortholog

CALB2

説明

A IRES-iCre expression cassette was knocked into the Calb2 gene stop codon site. Calb2 gene encodes calbindin 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. The protein plays a key role in the nervous system.
応用分野：Cre recombinase tool

表現型データ

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Fig. 1 Cre-mediated recombination in the pituitary gland of Calb2Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the hippocampus, cortex, olfactory bulb and cerebellar purkinje cells of Calb2Cre/+; Rosa26tdTomato/+ mouse.

image.png

Fig. 2 Detection of tdTomato(red) in various tissues of  Calb2Cre/+; Rosa26tdTomato/+ mice. Tdtomato expression can be detected in the brain, heart, lung, liver, stomach, kidney, pancreas, intestine, testis, epididymis, spleen, esophagus, thymus and colon.  (For more detailed information please contact our technical advisor.)


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