Pbsn-2A-CreERT2

系統名

C57BL/6Smoc-Pbsnem1(V5-2A-CreERT2-WPRE-polyA)Smoc

SMOC番号

NM-KI-200190

維持形態

Sperm cryopreservation

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遺伝子の概要

Gene Symbol
Pbsn

Synonyms

PB; Prbs

NCBI ID

54192

MGI ID

1860484

Ensembl ID

ENSMUSG00000000003

Pubmed

Pbsn

Human Ortholog

PBSN

説明

A V5-2A-CreERT2-WPRE-polyA expression cassette was knocked into the Pbsn gene stop codon site.
応用分野：Cre recombinase tool,epithelial cells of the prostate.

表現型データ

pbsn.png

Fig1. Expression Pattern of Tomato in PbsnCreERT2/+;Rosa26tdTomato/+ mice.

CreERT2-mediated recombination in prostate epithelial cells of PbsnCreERT2/+ ; Rosa26tdTomato/+ mice. This strain represents an effective tool for generating prostate specific-targeted mutants.

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Fig2. Cre mediated recombination in prostate of PbsnCreERT2/+;Rosa26tdTomato/+ mouse. 

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Fig3. Detection of tdTomato(red) in various tissues of PbsnCreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: prostate, salivary gland. A few cells expressed in adrenal gland, pancreas, testis, muscle and thymus. Tissues that unexpressed include brain, spinal cord, eyeball, heart, lung, liver, stomach, brown fat, kidney, colon, small intestine, spleen, and skin. (9-week old, male) (For more detailed information please contact our technical advisor.)

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