Epcam-2A-CreERT2

系統名

C57BL/6Smoc-Epcamem1(2A-CreERT2)Smoc

SMOC番号

NM-KI-00084

維持形態

Embryo cryopreservation

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遺伝子の概要

Gene Symbol
Epcam

説明

An 2A-CreERT2 co-expression cassette is inserted before 3'UTR region of Epcam gene .

表現型データ

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Fig1 CreERT2-mediated recombination in kidney cells of Epcam CreERT2+/-;R26 tdTomato+/- mice. Detection of tdTomato epifluorescence (red) and co-immunostaining for Epcam (green) in kidney cells of Epcam CreERT2+/- ;R26 tdTomato+/- mice.

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Fig2 CreERT2-mediated recombination in liver of Epcam-CreERT2+/-;R26 tdTomato+/- mice.

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Fig3 CreERT2-mediated recombination in small Intestines of Epcam-CreERT2+/-;R26 tdTomato+/- mice.

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Fig4 CreERT2-mediated recombination in large Intestines of Epcam-CreERT2+/-;R26 tdTomato+/- mice.


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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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