Ccr2-KO

系統名

C57BL/6Smoc-Ccr2em1Smoc

SMOC番号

NM-KO-190018

維持形態

Repository Live

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遺伝子の概要

Gene Symbol
Ccr2

説明

This Ccr2 knockout mouse model was generated by knocking out the exon 3 region of the Ccr2 .
応用分野:Immune-related

表現型データ

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Fig1. Validation of Ccr2 gene expression by RT-PCR.(A) Schematic diagram of primer design; (B) No product was obtained from Ccr2 knockout homozygous mice, and the wild-type mice could obtain the 824bp target PCR product. (M, DNA marker; HO, homozygous; WT, wild type)


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Fig2. Validation of  CCR2 expression in the bone marrow by FACS. CCR2 expression could not be detected on CD11b+ cells of the Ccr2 knockout homozygous mice. 


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Fig3. Validation of CCR2 expression in the spleen by FACS. CCR2 expression could not be detected on CD11b+ cells of the Ccr2 knockout homozygous mice. 



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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

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