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Models

Point Mutation Knockins

Point mutant knockin mouse model is a mouse in which one or more nucleotides are replaced by mutant nucleotides in the genome. This may result in amino acid changes within the protein sequence, and transcription terminated, thereby significantly affecting the normal function of the protein. Point mutation mouse models are widely used to study the role of specific nucleotides or amino acids in genetic elements or proteins, as well as to mimic human genetic diseases.

マウス
Trpm8-S966A
系統名：C57BL/6JSmo-Trpm8em1(S966A)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-190101
応用分野：Cation channel
マウス
Ttr-G103R
系統名：B6;129S-Ttrtm1(G103R)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-00134
マウス
Vps54-L967Q
系統名：C57BL/6JSmo-Vps54em1(L967Q)/Smoc
維持形態：Developing | SMOC番号：NM-KI-232086
マウス
Wap-Trp53*R172H-Tg
系統名：C57BL/6JSmo-Tg(Wap-P53(R172H))1Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-TG-220193
マウス
Zap70-W163C(Balb/c)
系統名：BALB/cJSmo-Zap70em(W163C)Smoc
維持形態：Repository Live | SMOC番号：NM-KI-210366
病気の予測：rheumatoid arthritis
マウス
Zbtb46-T11A
系統名：C57BL/6JSmo-Zbtb46em(T11A)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-215097
マウス
1110025M09Rik-S6x
系統名：C57BL/6JSmo-1110025M09Rikem(S6X)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-215102
マウス
2210010C04Rik-D23A
系統名：C57BL/6JSmo-2210010C04Rikem1D23ASmoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-232248
マウス
9030622O22Rik-c.T376C
系統名：C57BL/6JSmo-9030622O22Rikem1(T-376C)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-KI-200291
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