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Models

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

マウス
hTSHR(2)
系統名：C57BL/6JSmo-Tshrtm2(hTSHR)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-232157
マウス
hTSLP
系統名：C57BL/6JSmo-Tslptm2(hTSLP)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-2000064
応用分野：Asthma research；drug screening
マウス
hTSLP(NMG)
系統名：NOD.Cg-PrkdcscidIl2rgem1Tslptm(hTSLP)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220426
マウス
hTSLP/hIL17RA
系統名：C57BL/6JSmo-Tslptm2(hTSLP)Il17rtm1(hIL17R)/Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-200269
マウス
Htt-hHTTQ145
系統名：C57BL/6JSmo-Htttm1(hHTTQ145)Smoc
維持形態：Sperm cryopreservation | SMOC番号：NM-KI-234514
マウス
hTTR
系統名：C57BL/6JSmo-Ttrtm1(hTTR)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-225087
マウス
hTTR-V30M(p.V50M)
系統名：C57BL/6JSmo-Ttrtm(hTTR-V50M)Smoc
維持形態：Embryo cryopreservation | SMOC番号：NM-HU-220587
マウス
hTWEAK/hAPRIL
系統名：C57BL/6JSmo-Tnfsf12/Tnfsf13tm1(hTNFSF12/hTNFSF13)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-234421
マウス
hUGT1A1
系統名：C57BL/6JSmo-Ugt1a1tm1(hUGT1A1)Smoc
維持形態：Repository Live | SMOC番号：NM-HU-232902
マウス
huHSC-(NMG)
系統名：huHSC-(M-NSG)
維持形態：Repository Live | SMOC番号：NM-NSG-017
応用分野：Infectious disease; Gene therapy; Cancer; Drug targets without cross-reactivity; Immunogenicity study
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